Disorders of the liver, the most important metabolic organ, can affect the whole body. The liver receives almost all the blood from the intestines via the portal vein, which means that foodstuffs absorbed in the intestine pass through the liver first. It plays a major role in the metabolism of sugars (including sugar storage), and in the conversion of amino acids, from which protein is built up. The liver gives out metabolic breakdown products (ammonia), and converts bilirubin, a breakdown product of the red blood cells, into a form in which it can be discharged via the gall bladder in the bile. Other Accumulated fat in the liver shows on an X-ray as round globules containing fat.