Parkinson’s disease is created by a lack of a neurotransmitter called dopamine in the central nervous system. Treatment is by replacing this with a compound called levodopa, which when given in the right quantities is a safe drug to take. Another drug called dopa-decarboxylase inhibitor prevents natural dopamine from being broken down. The two in combination help people with Parkinson’s disease and can be a very effective treatment.
The problem lies in the fact that the body gets used to these compounds and after a few years may no longer respond. New drugs are constantly being brought in, such as selegiline, lysuride, amantadine and pergolide. All are beneficial but avoid the use of these drugs until alternative avenues have not succeeded. Use these drugs as late in the condition as possible because resistance to their efficacy will develop and lead to a decrease in usefulness after five to ten years.